Atherosclerosis - Cardiovascular Disorders - Merck Manuals Professional Edition. George Thanassoulis, MD, MSc, Director, Preventive and Genomic Cardiology; Assistant Professor, Department of Medicine, Mc. Atherosclerosis -- or hardening of the arteries -- is the leading cause of heart attacks, stroke, and peripheral vascular disease. Find out more. Atherosclerosis information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. High Cholesterol (Hypercholesterolemia) - an easy to understand guide covering causes, diagnosis, symptoms, treatment and prevention plus additional in depth medical. Gill University Health Centre; Mc. Gill University; Mehdi Afshar, MD, Resident, Department of Internal Medicine, Mc. Gill University. Click here for. Patient Education(See also Nonatheromatous Arteriosclerosis.)Atherosclerosis is characterized by patchy intimal plaques (atheromas) that encroach on the lumen of medium- sized and large arteries; the plaques contain lipids, inflammatory cells, smooth muscle cells, and connective tissue. Risk factors include dyslipidemia, diabetes, cigarette smoking, family history, sedentary lifestyle, obesity, and hypertension. Symptoms develop when growth or rupture of the plaque reduces or obstructs blood flow; symptoms vary by artery affected. Diagnosis is clinical and confirmed by angiography, ultrasonography, or other imaging tests. Treatment includes risk factor, lifestyle, and dietary modification, physical activity, antiplatelet drugs, and antiatherogenic drugs. Atherosclerosis is the most common form of arteriosclerosis, which is a general term for several disorders that cause thickening and loss of elasticity in the arterial wall. Atherosclerosis is also the most serious and clinically relevant form of arteriosclerosis because it causes coronary artery disease and cerebrovascular disease. Nonatheromatous forms of arteriosclerosis include arteriolosclerosis and M. It is the leading cause of morbidity and mortality in the US and in most developed countries. In recent years, age- related mortality attributable to atherosclerosis has been decreasing, but in 2.
CVD), primarily coronary and cerebrovascular atherosclerosis still caused almost 1. In the US, > 8. CVD in 2. 01. 4, corresponding to almost 1 in 3 of all deaths (2). Atherosclerosis is rapidly increasing in prevalence in developing countries, and as people in developed countries live longer, incidence will increase. Atherosclerosis is the leading cause of death worldwide.
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